Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B，H，K，L，O，and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis，protein degradation，and apoptosis. Cathepsin K expression is highest in bone，cartilage，and skeletal muscle.
应用类型
Western blotting （0.5-4 ug/ml）， immunoprecipitation， and Immunohistochemistry. However， the optimal conditions should be determined individually. The antibody detects proform （43 kDa） and the mature form （29 kDa） of cathepsin K.
免疫原
Synthetic peptide surrounding amino acid 321 of rat cathepsin K
