PPAR （Peroxisome proliferator-activated receptor） is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPAR is preferentially expressed in liver，skeletal muscle，heart and kidney. PPAR is involved in regulation of lipid homeostasis. Its ligands include fatty acids，NSAIDs，prostaglandins，leukotriene B4，etc. PPAR transcriptionally regulates a variety of genes for enzymes and proteins involved in fatty acid metabolism and oxidation.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes ~52 kDa PPAR in human sample. A ~28 kDa cleavage fragment can also be detected in samples of human， mouse， and rat origins.
免疫原
Synthetic peptide surrounding amino acid 25 of human PPAR
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠、绵羊、猪种属来源的PPAR-alpha蛋白 发生免疫反应.
保存建议
提供的PPAR-alpha抗体 产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该PPAR-alpha抗体 产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
