Wnt gene family members,including Wnt-1 throμgh Wnt-10,play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich,secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-3 is also involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 10 of human Wnt-4