TRADD （TNF-R1-associated death domain） is a 34 kDa protein that associates with the death domains of both FAS and TNF-R1 via their DDH regions. Overexpression of TRADD leads to NFκB activation and apoptosis in the absence of TNF.
应用类型
Western blotting （0.5-4 ug/ml）. Based on researchers feedback， it also works well in immunoprecipitation （10-20 ug/ml） and Immunohistochemistry （15-25 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes 34 kDa TRADD in samples from human， mouse， and rat origins. Reactivity to other species has not been tested. Mouse small intestine tissue lysate can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 300 of human TRADD
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的TRADD蛋白 发生免疫反应.
保存建议
提供的TRADD抗体 产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该TRADD抗体 产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
