Adipose tissue is an energy reserve in animals. Adipose cells produce and secrete numerous physiologically important proteins that help regulate whole body metabolism，such as adiponectin leptin. Fasting causes significant changes in nutrient metabolism and many of these changes are controlled by transcription factors that regulate rate-limiting enzymes. An important transcription factor that mediates metabolic processes induced by fasting is peroxisome proliferator-activated receptor alpha （PPAR alpha）. PPAR alpha has recently been reported to target a novel gene encoding the secreted protein FIAF （fasting-induced adipose factor）. FIAF is expressed predominantly in adipose tissue and is strongly upregulated in white adipose tissue and the liver under fasting conditions. Initial studies suggest that FIAF represents a novel endocrine signal helping to regulate metabolism，especially under fasting conditions.
应用类型
Western blotting （0.5-4 ug/ml）. It recognizes ~50 kDa FIAF from samples of mouse and rat origins.
免疫原
Synthetic peptide surrounding amino acid 84 of mouse FIAF
来源宿主
兔
反应性
经检测验证，可与小鼠、大鼠种属来源的FIAF蛋白 发生免疫反应.
保存建议
提供的FIAF抗体 产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该FIAF抗体 产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
