SOD (Superoxide Dismutase) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically,SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide,and it also catalyzes prooxidant reactions,which include the peroxidase activity and hydroxyl radical generating activity. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases.
应用类型
Western blotting (0.5-4 ug/ml), immunoprecipitation (20 ug/ml) and Immunohistochemistry (20 ug/ml, frozen & paraffin). However, the optimal concentrations should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 131 of human SOD
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的SOD-1蛋白 发生免疫反应.
保存建议
提供的SOD-1抗体 产品为100 ug 无色溶液,其浓度为0.2 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该SOD-1抗体 产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.