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中文名称

FOG9 (500 ug)

英文名字
5-OxoETE-glutathione, FOG9, 5-oxo-6Z,9S-(S-glutathionyl)-11Z,14Z-eicosatrienoic acid
供应商
Cayman
产品货号
34265-500
产品报价
¥23968/500 ug
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背景资料
FOG9 is formed through the conjugation of 5-oxoETE with glutathione in a 1,6 Michael addition at C-9. The biological activity of FOG9 has not been determined. However, FOG7, a 1,4-adduct formed within murine peritoneal macrophages, was found to be highly potent in stimulating eosinophil and neutrophil chemotaxis. FOG7 was also capable of initiating actin polymerization without elevating intracellular free calcium ion concentration within either the eosinophil neutrophils or PMNL.
产品描述
FOG9 is formed through the conjugation of 5-oxoETE with glutathione in a 1,6 Michael addition at C-9. The biological activity of FOG9 has not been determined. However, FOG7, a 1,4-adduct formed within murine peritoneal macrophages, was found to be highly potent in stimulating eosinophil and neutrophil chemotaxis.{8518} FOG7 was also capable of initiating actin polymerization without elevating intracellular free calcium ion concentration within either the eosinophil neutrophils or PMNL.
产品形式
保存建议
-80
其他
Cayman Chemical
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