Members of TRAF family associate with activated TNF-R and CD40 and have been implicated to induce nuclear translocation of NFkB. TANK can bind to all three TRAFs and synergizing with TRAF2 to activate the NFkB signal cascade.
应用类型
Western blot, Immunoprecipitation, Immunohistochemistry
免疫原
Synthetic peptide surrounding amino acid 413 of human TANK
