FAF1 （Fas-associated protein factor 1） specifically interacts with the cytoplasmic domain of wild type，but not mutated，Fas in both yeast and mammalian cells. When transiently expressed in T cells，FAF1 potentiates Fas-induced apoptosis. In contrast to TRADD，FADD，and RIP，FAF1 lacks a DDH （Death domain homologous region） and cannot induce apoptosis independent of Fas activation.
应用类型
Western blotting （0.5-4 ug/ml） and in immunoprecipitation and Immunohistochemistry. However， the optimal conditions should be determined individually. Rat kidney cell lysate can be used as a positive control.
免疫原
Synthetic peptide corresponding to residues surrounding amino acid 640 of human FAF1
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的FAF1蛋白发生免疫反应.
保存建议
提供的FAF1抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该FAF1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
