The caspase family of cysteine proteases play a key role in apoptosis. Like other caspases in the family，caspase-4 is also synthesized as inactive pro-enzyme that is processed in cells by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-4 consists of large and small subunits which associate to form an active enzyme. Caspase-4 has been implicated involving in Fas-mediated apoptosis.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. 293 cell lysate can be used as a positive control. Detects the 43 kDa human caspase-4
免疫原
Synthetic peptide corresponding to the N-terminus of human Caspase-4
来源宿主
小鼠
反应性
经检测验证，可与人种属来源的Caspase-4蛋白发生免疫反应.
保存建议
提供的Caspase-4抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有0.5% BSA， 1.5 mM 叠氮钠和30%甘油.的PBS缓冲液中.请将该Caspase-4抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
