ASC （also called TMS1） is a CARD domain containing protein. ASC induces apoptosis through activation of caspase-9 and inhibiting the survival of human breast cancer cells. Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The affinity purified antibody detects the 25 kDa human and rat ASC/TMS1. HL60 cell lysate can be used as a positive control.
免疫原
Synthetic peptide corresponding to residues surrounding amino acid 185 of human ASC
来源宿主
兔
反应性
经检测验证，可与人种属来源的ASC/TMS1蛋白发生免疫反应.
保存建议
提供的ASC/TMS1抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该ASC/TMS1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
