TCTN2 is a member of the Tectonic protein family. Tectonic proteins are transmembrane proteins that regulate the Hedgehog (Hh)-signaling pathway. Defects in TCTN2 can lead to Meckel syndrome type 8. This disorder is characterized by a combination of renal cysts and variable associated features which includes developmental anomalies of the central nervous system，hepatic ductal dysplasia and cysts，and polydactyly.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 435 of rat TCTN2
