TCTN2 is a member of the Tectonic protein family. Tectonic proteins are transmembrane proteins that regulate the Hedgehog （Hh）-signaling pathway. Defects in TCTN2 can lead to Meckel syndrome type 8. This disorder is characterized by a combination of renal cysts and variable associated features which includes developmental anomalies of the central nervous system，hepatic ductal dysplasia and cysts，and polydactyly.
应用类型
Western Blot analysis （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Blocking peptide （Cat.# 3262BP-50） is available separately.
免疫原
Synthetic peptide surrounding amino acid 435 of rat TCTN2
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的TCTN2蛋白发生免疫反应
保存建议
提供的100 ug TCTN2抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该TCTN2抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
