Akt,also referred to as PKB and RAC,is the cellular homologue of the viral oncogene v-Akt. This protein kinase is activated by insulin and various growth factors and functions in a pathway involving PI3 kinase as activation is sensitive to wortmanin. Recent evidence sμggests that Akt functions to promote cell survival by actively inhibiting apoptosis.
应用类型
Western blot,Immunoprecipitation, Immunohistochemistry
免疫原
Synthetic peptide corresponding to residue surrounding amino acid 80 of human Akt