Bcl-2 (B-cell leukemia/lymphoma 2) gene was discovered by walking the chromosomal breakpoints t(14;18). This gene consists of two exons and several transcripts that encode two different protein products,Bcl-2 and Bcl-2B. Both proteins are approximately 26-30 kDa and differ at their C-terminal region. Bcl-2 suppresses apoptosis (programmed cell death) and this property appears to be modulated by homodimerization or association with Bax and Bad,two cell death promoters
应用类型
Western blot (1-4 ug/ml), Immunoprecipitation, Immunohistochemistry, and Flow cytometry. However the optimal conditions should be determined individually. Recognize the 26 kDa human Bcl-2
免疫原
Synthetic peptide corresponding to resides surrounding a.a. 44 of Human Bcl-2
来源宿主
小鼠
反应性
经检测验证,可与人种属来源的Bcl-2 蛋白 发生免疫反应.
保存建议
提供的Bcl-2 抗体 产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有1 mg/ml BSA和1.5 mM 叠氮钠和50%甘油的PBS缓冲液中.请将该Bcl-2 抗体 产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.