Human perforin （cytolysin） is believed to be one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis. Perforin expression is constitutive on NK cells，but increases in resting XD8+ cytotoxic cells upon activation.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects ~70 kDa Perforin in samples from human， mouse and rat origins. Reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 568 of rat Perforin
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的Perforin蛋白发生免疫反应.
保存建议
提供的Perforin抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Perforin抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
