- 中文名称
Prostaglandin E1-d4 (5 mg)
- 英文名字
- Alprostadil-d4|PGE1-d4, Prostaglandin E1-d4, 9-oxo-11
- 供应商
- Cayman
- 产品货号
- 313010-5
- 产品报价
- ￥35280/5 mg
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- Prostaglandin E1-d4 (PGE1-d4) contains four deuterium atoms at the 3, 3 , 4, and 4 positions. It is intended for use as an internal standard for the quantification of PGE1 by GC- or LC-mass spectrometry. PGE1 is the theoretical cyclooxygenase metabolite of dihomo-.gamma.-linolenic acid (DGLA), but it is virtually undetectable in the plasma of normal humans or other animals. Its pharmacology includes vasodilation, hypotension, and anti-platelet activities. The IC50 of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM. The vasorelaxant and anti-hypertensive effects of PGE1 are used to treat male erectile dysfunction and to provide emergency vasodilation of the patent ductus arteriosus in infants whose cardiac anomalies require pulmonary shunting for survival. In human males, the intracavernosal effective dose range for PGE1 is 2 to 80 ug, and the transurethral range is 125 to 1,000 ug.
- 产品描述
- An internal standard for the quantification of PGE1 by GC- or LC-MS.
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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