Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play important roles in determining tissue specific cell fate during embryogenesis，like muscle or early B cell differentiation. Dimers bind DNA on E box motifs: 5' CANNTG 3'.Binds to the kappa E2 site in the kappa immunoglobulin gene enhancer.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 556 of rat TCF3/E2A
