Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play important roles in determining tissue specific cell fate during embryogenesis,like muscle or early B cell differentiation. Dimers bind DNA on E box motifs: 5’ CANNTG 3’.Binds to the kappa E2 site in the kappa immunoglobulin gene enhancer.
应用类型
Western Blot analysis (1 ug/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3090BP-50) is available separately.
免疫原
Synthetic peptide surrounding amino acid 556 of rat TCF3/E2A
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的TCF3/E2A蛋白发生免疫反应
保存建议
提供的100 ug TCF3/E2A抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油, 0.5% BSA, 5 mM EDTA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该TCF3/E2A抗体产品置于-20 °C冷冻保存,建议分装使用以避免反复冻融.