MBD4 （methyl-CpG-binding domain protein 4） belongs to the MBD family of nuclear proteins that bind to methylated CpG sites and represses gene transcription. Human proteins MECP2，MBD1，MBD2，and MBD4，except MBD3 bind specifically to methylated DNA. MBD4 exhibits thymine glycosylase activity and is known to play an important function in DNA mismatch repair and apoptosis.
应用类型
The antibody can be used in Western Blot analysis （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 474 of mouse MBD4
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的MBD4蛋白发生免疫反应
保存建议
提供的100 ug MBD4抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该MBD4抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
