Bak is a homolog of apoptosis inhibitor Bcl-2. Bak is a member of the Bcl-2 family of proteins and contains Bcl-2 homology region (BH-) 1,2 and 3. Unlike Bcl-2,Bak promotes cell death and counteracts the anti-apoptotic effect of Bcl-2. The immunoaffinity purified antibody detects a 30 kDa band,corresponding to the expected molecular weight of Bak on SDS-PAGE immunoblots.
应用类型
Western blot
免疫原
Synthetic peptide mapping the N-terminus of human BAK1