Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674)
应用类型
ELISA, WB, IF
免疫原
human GFRa-1
来源宿主
鸡
反应性
Human GFRa-1 doesn’t cross-react with hGFRa-2, hGFRa-3, hGFRa-4
保存建议
Store at +4 °C upon receipt. As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use
