EZSolution TAPI-1(1毫克)产品是Inhibitor of TNF-α processing (IC₅₀ = 100 nM), similar to TAPI-0 (Cat. No. 2067-1), but more stable in tissue culture and in vivo. Inhibits TACE and other metalloproteases. Blocks release of TNF- α (IC₅₀ = 50-100 uM), APP (1-8 uM), IL6R (5- 10 uM), TNFRI (5 -10 uM), TNFRII (25 -50 uM), and ObRa (leptin receptor), but not CSF-1, from cells in culture.