Daminozide (JHDM Inhibitor VI, N,N-Dimethylamino-succinamic Acid, Succinic Acid-2,2-dimethylhydrazide, 4-(2,2-Dimethylhydrazinyl)-4-oxobutanoic Acid, BHC100 Inhibitor VI, KDM2A Inhibitor, KIAA1718 Inh-Daminozide (JHDM Inhibitor VI, N,N-Dimethylamino-succinamic Acid, Succinic Acid-2,2-dimethylhydrazide, 4-(2,2-Dimethylhydrazinyl)-4-oxobutanoic Acid, BHC100 Inhibitor VI, KDM2A Inhibitor, KIAA1718 Inhibitor VI, LSD Inhibitor VI, PHF8 Inhibitor, Histo-生化试剂-艾美捷科技有限公司

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中文名称: Daminozide (JHDM Inhibitor VI, N,N-Dimethylamino-succinamic Acid, Succinic Acid-2,2-dimethylhydrazide, 4-(2,2-Dimethylhydrazinyl)-4-oxobutanoic Acid, BHC100 Inhibitor VI, KDM2A Inhibitor, KIAA1718 Inh

英文名字: Daminozide (JHDM Inhibitor VI, N,N-Dimethylamino-succinamic Acid, Succinic Acid-2,2-dimethylhydrazide, 4-(2,2-Dimethylhydrazinyl)-4-oxobutanoic Acid, BHC100 Inhibitor VI, KDM2A Inhibitor, KIAA1718 Inhibitor VI, LSD Inhibitor VI, PHF8 Inhibitor, Histo

背景资料: USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！

产品描述: A dimethylamino substituted succinamate that, in addition to its well known use as a plant growth regulator, also acts as an inhibitor against histone lysine demthylases KDM2A, LSD1 (KDM7A; KIAA1718), and PHF8 (IC50 = 1.5, 2.1, and 0.55uM, respectively), but not KDM3A, KDM4E, KDM5C, KDM6B, or three hydroxylases (IC50 >100uM). Substrate-competition and/or active site Iron chelating likely accounts for the inhibitory activity against the FAD-dependent LSD1, while 2-oxoglutarate (2-OG) competition (Ki = 1.97uM) appears as the major mode of action against KDM2A.Formula:C6H12N2O3Solubility:H2OMolar Mass:160.2Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

保存建议: 接收到Daminozide (JHDM Inhibitor VI, N,N-Dimethylamino-succinamic Acid, Succinic Acid-2,2-dimethylhydrazide, 4-(2,2-Dimethylhydrazinyl)-4-oxobutanoic Acid, BHC100 Inhibitor VI, KDM2A Inhibitor, KIAA1718 Inhibitor VI, LSD Inhibitor VI, PHF8 Inhibitor, Histone Lysine Demethylase Inhibitor XII, LSD1 Inhibitor VI)产品后，置于4°C温度下保存。

其他: Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。