- 中文名称
20-hydroxy Leukotriene B4 (500 ug)
- 英文名字
- 2-hydroxy LTB4, 20-hydroxy Leukotriene B4, 5S,12R,2-trihydroxy-6Z,8E,1E,14Z-eicosatetraenoic acid
- 供应商
- Cayman
- 产品货号
- 20190-500
- 产品报价
- ￥30016/500 ug
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- 20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki = 13.3 nM). However, 20-hydroxy LTB4 is as active as LTB4 in contracting parenchymal strips from guinea pig lung. 20-hydroxy LTB4 retains considerable ligand binding affinity at the BLT2 receptor, but does not appear to function as an agonist.
- 产品描述
- 20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL,{399} but actually inhibits LTB4-induced degranulation of human neutrophils (Ki = 13.3 nM).{1106} However, 20-hydroxy LTB4 is as active as LTB4 in contracting parenchymal strips from guinea pig lung.{377} 20-hydroxy LTB4 retains considerable ligand binding affinity at the BLT2 receptor,{8743,9270} but does not appear to function as an agonist.{8525}
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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