QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be downregulated in the brain of schizophrenic patients. Anti-QKI (pan) is ideal for research in Neuroscience and Gene Expression.
应用类型
ELISA,Immunohistochemistry,Western Blot,
免疫原
Anti-QKI (pan) Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 1-341 (full length) of human QKI-5.
来源宿主
Mouse
反应性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建议
Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.