Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells. The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons. This antibody is suitable for researchers interested in neurodegenerative diseases, developmental signaling, GPCR signaling, and MAK Kinase Signaling.
应用类型
ELISA,Immunohistochemistry,Western Blot,
免疫原
Caldesmon (smooth) antibody was produced in mice by repeated immunizations with human uterus smooth muscle extract.
来源宿主
Mouse
反应性
H. sapiens (Human); Leporidae (Rabbit); Mus musculus (Mouse)
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
