Depolarization-activated postassium channels (Kv) play a major role in shaping the electrical signals in the nervous system. KvBeta2, otherwise known as potassium voltagegated channel, shaker-related subfamily beta member 2, is encoded by the KCNAB2 gene in humans. The KvBeta channels are also members of the aldo-keto reductase (AKR) subfamily. These proteins regulated inactivation and membrane localization of Kv1 and Kv4 channels. Specifically Kv2beta2 contributes to regulation of excitability in vivo, although not directly through either chaperone-like or typical AKR catalytic activity.
KvBeta2 K+ channel Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to the full length of rat Kvβ2.
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
