Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene. It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion. The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel.
应用类型
Immunohistochemistry,IF Microscopy,Western Blot,
免疫原
Kv1.1 Antibody was produced in mice by repeated immunizations raised against a synthetic peptide at a cytoplasmic C-terminus of rat Kv1.1.
来源宿主
Mouse
反应性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
