Syntaxin antibody detects Syntaxin-1A protein which is part of a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion. Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia. Anti-Syntaxin Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
应用类型
Immunohistochemistry,Western Blot,
免疫原
Anti-Syntaxin Monoclonal Antibody was produced in mouse by repeated immunizations with Synaptic immunoprecipitate (crude) from human brain.
来源宿主
Mouse
反应性
Cricetinae (Hamster); H. sapiens (Human); Rattus (Rat); Sus scrofa domesticus (Pig, Porcine, Swine)
保存建议
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
