COBRA 1 antibody reacts with COBRA1 (cofactor of BRCA1) also known as NELF-B, which is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription. COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis. Anti-COBRA 1 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
应用类型
ELISA,Western Blot,
免疫原
Anti-COBRA1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant full length human COBRA1 purified from E.coli.
来源宿主
Mouse
反应性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建议
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
