- 中文名称
TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)
- 英文名字
- TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)
- 供应商
- USBiological
- 产品货号
- 169750
- 产品报价
- ¥1/1Kit
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理,是行业中少有的致力于服务客户,帮助客户,且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应,专业的产品和解决方案支持,稳健快捷的交货周期,优质放心的售后服务。我们致力于为您提供有价值的产品和服务,在意您的成功!
- 产品描述
- The TACE (tumor necrosis factor-alpha-converting enzyme), also called ADAM Metallopeptidase domain 17 (ADAM17), is a 70kD enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases. TACE is believed to be involved in the processing of tumor necrosis factor alpha (TNF-alpha) at the surface of the cell, and from within the intracellular membranes of the trans-Golgi network. This process, which is also known as 'shedding', involves the cleavage and release of a soluble ectodomain from membrane-bound pro-proteins (such as pro-TNF-alpha), and is of known physiological importance.Intended Use:TACE hydrolyzes the specific FRET substrate to release the quenched fluorescent group, which can be detected fluorometrically at Ex/Em = 318/449nm.Specificity:MammalianTest Principle:In the presence of the potent TACE inhibitor, the hydrolyzation of substrate will be impeded. The kit provides a rapid, simple, sensitive and reliable test suitable for high-throughput screening of TACE inhibitors and can be modified to check the relative TACE activity. Inhibitor Control GM6001 is included to compare the efficacy of test inhibitors.Kit Components:Assay buffer, 1x25mlSubstrate, 1x0.2mlEnzyme (20ug), 1x1vialInhibitor Control, 1x20ulStorage and Stability:Store powder at 4°C, liquid at -20°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- 产品特点
- 针对TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)该产品的特点优势,欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)产品后将其置于-20°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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