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中文名称

Cicaprost (10 mg)

英文名字
ZK 9648, Cicaprost, 2-[2-[(2E,3aS,4S,5R,6aS)-hexahydro-5-hydroxy-4-[(3S,4S)-3-hydroxy-4-methyl-1,6-nonadiyn-1-yl]-2(1H)-pentalenylidene]ethoxy]-acetic acid
供应商
Cayman
产品货号
16831-10
产品报价
¥35868/10 mg
产品说明书
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背景资料
Prostaglandin I2 -PGI2, prostacyclin) is the most potent endogenous vasodilator that affects both the systemic and pulmonary circulation. Cicaprost is a PGI2 analog that is orally active with prolonged availability in vivo, having a terminal half life in plasma of one hour. In addition to their effects on smooth muscle, PGI2 analogs, including cicaprost, have been shown to inhibit the pro-inflammatory actions of certain leukocytes, suppress cardiac fibrosis, and block mitogenesis of certain cell types. Importantly, cicaprost has been shown to strongly reduce lung and lymph node metastasis in rats, suggesting that it might be useful in cancer therapy.
产品描述
A prostacyclin analog that is orally active with prolonged availability in vivo, having a terminal half-life in plasma of one hour; inhibits the pro-inflammatory actions of certain leukocytes, suppresses cardiac fibrosis, and blocks mitogenesis of certain cell types
产品形式
保存建议
-20
其他
Cayman Chemical
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