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中文名称

抗15-hydroxy Prostaglandin Dehydrogenase 脱氢酶多克隆抗体

英文名字
15-hydroxy Prostaglandin Dehydrogenase Polyclonal Antibody
供应商
Cayman
产品货号
160615-500
产品报价
¥2254/500 μl
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背景资料
NAD+-dependent 15-hydroxy PGDH catalyzes the oxidation of prostaglandins to 15-keto metabolites, which have greatly reduced biological activity. Human NAD+-dependent 15-hydroxy PGDH is a 266 amino acid protein with a molecular weight of 29 kDa and is expressed in multiple tissues including lung, placenta, and kidney. The enzyme belongs to a large family of short-chain alcohol dehydrogenases, which exhibit amino acid identity ranging from 15-30%. An NADP+-dependent 15-hydroxy PGDH, which is also part of this enzyme family, exhibits only 20% amino acid identity to the NAD+-dependent enzyme. The peptide used as the antigen for preparation of the 15-hydroxy PGDH antibody is highly conserved across several species -see above), but has only minor homology to other proteins within the short-chain alcohol dehydrogenase family of enzymes -only the alanine and glycine at the N-terminus of the sequence appear to be conserved).
应用类型
WB; other applications not tested
免疫原
human NAD+-dependent 15-hydroxy prostaglandin dehydrogenase -15-hydroxy PGDH) amino acids 92-105 -AGVNNEKNWEKTLQ){387}
来源宿主
rabbit
反应性
Human 15-hydroxy PGDH+|Bovine 15-hydroxy PGDH+|Guinea pig 15-hydroxy PGDH+|Baboon 15-hydroxy PGDH+
保存建议
其他
Cayman Chemical
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