- 中文名称
11-deoxy-11-methylene-15-keto Prostaglandin D2 (5 mg)
- 英文名字
- 11-deoxy-11-methylene-15-keto PGD2, 11-deoxy-11-methylene-15-keto Prostaglandin D2, 9.alpha.-hydroxy-11-methylene-15-oxo-prosta-5Z,13E-dien-1-oic acid
- 供应商
- Cayman
- 产品货号
- 12415-5
- 产品报价
- ￥22540/5 mg
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Prostaglandin D2 -PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. Many of the biological effects of PGD2 are transduced in vivo by a classical 7-transmembrane GPCR, the DP1 receptor. However, a second receptor, the chemokine-related CRTH2 receptor, also binds PGD2. This new receptor was recently identified on human eosinophils, where it binds selectively the PGD2 metabolite 13,14-dihydro-15-keto PGD2. 11-deoxy-11-methylene-15-keto PGD2 was prepared as a more chemically stable ligand for this receptor. There are no published studies of the pharmacological properties of 11-deoxy-11-methylene-15-keto PGD2.
- 产品描述
- PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. Many of the biological effects of PGD2 are transduced in vivo by a classical 7-transmembrane GPCR, the DP1 receptor.{3128} However, a second receptor, the chemokine-related CRTH2 receptor, also binds PGD2.{10058,10722} This new receptor was recently identified on human eosinophils, where it binds selectively the PGD2 metabolite 13,14-dihydro-15-keto PGD2.{9769} 11-deoxy-11-methylene-15-keto PGD2 was prepared as a more chemically stable ligand for this receptor. There are no published studies of the pharmacological properties of 11-deoxy-11-methylene-15-keto PGD2.
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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