Mouse VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF (isoform 164) is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains.
应用类型
WB, IHC
免疫原
该Anti-Mouse VEGF-A的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Mouse VEGF-A的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Mouse VEGF-A的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Mouse VEGF-A的详细信息查看ReliaTech提供的产品说明书。溶解建议:Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.