Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.
应用类型
WB
免疫原
该Anti-Mouse Granzyme B的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Mouse Granzyme B的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Mouse Granzyme B的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Mouse Granzyme B的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
