The antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.
应用类型
IHC (P), FC, IP
免疫原
该Anti-Mouse LPAM-1的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Mouse LPAM-1的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Mouse LPAM-1的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Mouse LPAM-1的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
