Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which maintains pluripotency and self renewal via a STAT3 independent pathway. Recombinant human Nanog is a 35 kDa protein, which is synthesized as a 304 amino acid polypeptide lacking a signal sequence for secretion.
应用类型
ELISA, WB
免疫原
该Anti-Human Nanog的详细信息查看ReliaTech提供的产品说明书。
来源宿主
Rabbit
反应性
该Anti-Human Nanog的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human Nanog的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
