TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.
应用类型
ELISA
免疫原
该Anti-Human TRAIL/Apo2L的详细信息查看ReliaTech提供的产品说明书。
来源宿主
Mouse
反应性
该Anti-Human TRAIL/Apo2L的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human TRAIL/Apo2L的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
