Indian Hedgehog (Ihh), Sonic Hedgehog (Shh), and Desert Hedgehog (Dhh) are important signaling molecules during embryonic development and are highly conserved within and across species. Mouse Ihh cDNA encodes a 411 amino acid (aa) polypeptide with a predicted 27 aa signal peptide. Post-translational processing yields a 19 kDa lipid-modified N-terminal domain that is the signaling molecule. At the cell surface, Ihh activity is mediated by binding the 12-pass transmembrane receptor, Patched (Ptc), and signaling through the 7-pass transmembrane G-protein coupled receptor, Smoothened (Smo).
应用类型
WB
免疫原
该Anti-human Indian Hedgehog的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-human Indian Hedgehog的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-human Indian Hedgehog的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-human Indian Hedgehog的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
