Osteoprotegerin (OPG)/osteoclastogenesis inhibitory factor (OCIF) is a member of the TNF receptor superfamily and is now referred to as TNFRSF11B. It is an osteoblast secreted decoy receptor that binds specifically to osteoprotegrin ligand (OPGL/TNFSF11) to inhibit osteoblast maturation. It is also a decoy receptor for TRAIL and inhibits TRAIL-induced apoptosis. Human and mouse OPG share approximately 84% and 94% amino acid sequence identity, respectively, with rat OPG. Natural OPG exists predominantly as disulfide-linked dimers.
应用类型
WB, N
免疫原
该Anti-Human TNFRSF11B的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human TNFRSF11B的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human TNFRSF11B的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human TNFRSF11B的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
