TIM-1 (T cell-immunoglobulin-mucin; also KIM-1 and HAVcr-1) is a 100 kDa, type I transmembrane glycoprotein member of the TIM family of immunoglobulin superfamily molecules. This gene family is involved in the regulation of Th1 and Th2 cell mediated immunity. Human TIM-1 is synthesized as a 359 amino acid (aa) precursor that contains a 20 aa signal sequence, a 270 aa extracellular domain (ECD), a 21 aa transmembrane segment and a 48 aa cytoplasmic domain. The ECD contains one V-type Ig like domain and a mucin region characterized by multiple PTTTTL motifs. The mucin region undergoes extensive O-linked glycosylation.
应用类型
WB, IHC (P)
免疫原
该Anti-Human TIM-1的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human TIM-1的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human TIM-1的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human TIM-1的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
