The synuclein family (SNCA) includes synuclein-alpha, -beta, and -gamma, and synoretin. These small, highly conserved proteins are localized predominantly in the brain, concentrated in presynaptic nerve terminals. Synuclein-alpha is normally a soluble protein. Abnormal synuclein-alpha forms filamentous inclusions (Lewy bodies and Lewy neurites) in several neurodegenerative diseases, including Parkinson's disease (PD), dementia with Lewy bodies, and Alzheimer's disease. Synucleins beta and gamma (synoretin) associate with synuclein-alpha and inhibit its aggregation.
应用类型
WB
免疫原
该Anti-Human SNCA的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human SNCA的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human SNCA的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human SNCA的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
