Pin1 is a peptidylprolyl isomerase (PPI) that targets phosphorylated Ser or Thr residues followed by a Pro (S/TP). Isomerization of phosphorylated Ser or Thr residues may alter protein confirmation and, subsequently, modify activity. Pin1 is overexpressed in many human breast cancers, and has been shown to modify numerous proteins including p53,NFκB, cJun, cyclin D1, and βcatenin.
应用类型
WB
免疫原
该Anti-Human PIN的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human PIN的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human PIN的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human PIN的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
