NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.
应用类型
WB, IHC (F), FC
免疫原
该Anti-Human NKp46的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human NKp46的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human NKp46的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human NKp46的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
