NKG2A and NKG2C are type II transmembrane proteins with extracellular C-type lectin domains. These proteins heterodimerize with CD94 to form complexes that recognize HLA-E as ligand. The NKG2A/CD94 complex delivers an inhibitory signal resulting from ITIMs within the NKG2A cytoplasmic domain. NKG2C/CD94 provides an activating signal due to association with the ITAM-containing DAP12 adapter protein. These complexes are expressed on NK and T cell subsets.
应用类型
WB
免疫原
该Anti-Human NKG2A的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human NKG2A的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human NKG2A的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human NKG2A的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
