β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 14 kDa polypeptide monomers (240 total amino acid residues). The three disulfide bonds are required for biological activity.
应用类型
ELISA, N
免疫原
该Anti-Human NGF-beta的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human NGF-beta的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human NGF-beta的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human NGF-beta的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
