The insulin receptor is a type I transmembrane receptor tyrosine kinase. Ligand binding results in receptor autophosphorylation, and subsequent downstream signaling important in metabolic regulation, cell growth, differentiation, and apoptosis. Mutations in the insulin receptor gene have been linked to insulin-resistant diabetes mellitus and noninsulin-dependent diabetes mellitus.
应用类型
WB
免疫原
该Anti-Human Insulin R的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human Insulin R的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human Insulin R的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human Insulin R的详细信息查看ReliaTech提供的产品说明书。溶解建议:Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.