GDNF family receptor alpha-1 is a protein that in humans is encoded by the GFRA1 gene. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
应用类型
WB
免疫原
该Anti-Human GDNF R alpha 2的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human GDNF R alpha 2的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human GDNF R alpha 2的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human GDNF R alpha 2的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
